Streptococcus pneumonia (S. pneumoniae) was first isolated from the sputum of patients in France and the United States by Louis Pasteur and G. M. Sternberg in 1881. It is a Gram-positive, spearhead like, double or short chain like diplococcus. The toxic strain has a capsule with a chemical component of polysaccharide in vitro. Most S. pneumoniae serotypes can cause disease.
Fig.1 S. pneumoniae under electron microscope.
S. pneumoniae mainly causes human lobar pneumonia. Its main pathogenic substances are pneumococcal hemolysin and capsule. The capsule has antigenicity, which is the basis of S. pneumoniae typing. It can cause lobar pneumonia, meningitis, bronchitis and other diseases.
Laboratory examination of streptococcus pneumoniae includes sample collection, bacteriological examination, isolation and culture, identification test and mouse virulence test. Polymerase chain reaction (PCR) detection and fluorescent labeled antibody detection can improve the level of pathogenic diagnosis.
As a professional and experienced biotechnology company with excellent research team, Creative Biogene is able to proceed detection of streptococcus pneumonia in sputum, pus, blood, cerebrospinal fluid and other specimens with PCR technique, and comprehensive data analysis can also be provided with our powerful bioinformatics platform.
A positive test for streptococcus pneumoniae indicates infection with pneumococcus. A negative test result indicates that there is no current or recent pneumococcal infection.