Deoxyribo Nucleic Acid (DNA) is a type of nucleic acid, one of the four biological macromolecules contained in living cells. DNA carries genetic information necessary for the synthesis of RNA and proteins, and is a biological macromolecule essential for the development and proper functioning of living organisms. DNA consists of a macromolecular polymer composed of deoxyribonucleotides. Deoxyribonucleotides are composed of bases, deoxyribose and phosphate. There are four of these bases: adenine (A), guanine (G), thymine (T) and cytosine (C).
In the structure of the DNA molecule, two polydeoxyribonucleotide chains are coiled around a common central axis, forming a double helix structure. The deoxyribose-phosphate chain is on the outside of the helix structure, with the bases facing inward. The two polydeoxyribonucleotide chains are complementary in reverse and are linked by base pairing formed by hydrogen bonds between the bases, forming a fairly stable assembly.
Prior to cell division, the DNA replication process copies genetic information, which avoids the loss of genetic information during transitions between cell generations. In eukaryotes, DNA is found in structures called chromosomes in the nucleus of the cell. In other organisms that do not have a nucleus, DNA is found either in chromosomes or in other tissues (bacteria have single-loop double-stranded DNA molecules, while viruses have DNA or RNA genomes). In chromosomes, chromatin proteins such as histones, coexisting proteins and cohesion proteins hold DNA in an ordered structure. These structures direct the interactions between the genetic code and the proteins responsible for transcription and help control the transcription of genes.
In terms of years' professional experience in this field, Creative Biogene can provide you with quick and easy DNA extraction.
Figure 1. The process of DNA extraction.
Creative Biogene can provide the DNA extraction technology meeting the following requirements:
Creative Biogene can extract genomic DNA from multi-species, large range of samples such as tissues, cells, blood, viruses, plants, FFPE, oral mucosal cells, bacteria. Perfectly reproducible DNA extraction for a wide range of basic downstream molecular biology experiments, including DNA cloning, DNA sequencing, DNA electrophoresis and PCR.