Circular Oligonucleotides Synthesis

Circular oligonucleotides are covalently closed single DNA or RNA strands. Compared with their linear structures, circular oligonucleotides are more resistant to nucleases and can resist degradation by many cellular DNA and RNA decay mechanisms. Circular DNA oligonucleotides or circular RNA oligonucleotides can be chemically synthesized using a part of linear precursor as a substrate by solution and solid-phase synthesis methods and then used in the fields of diagnosis and therapy.

Circular Oligonucleotides Synthesis

Circular Oligonucleotides Synthesis

As a professional biotechnology company, Creative Biogene can provide you with the synthesis and modified services of certain sequence circular oligonucleotides. After removing the linear DNA from the final compound, we use PAGE to purify the synthesized circular oligonucleotide to achieve the required purity. We also use mass spectrometry to analyze the quality of the final product to ensure that you get high-quality products. In addition, our scientists will provide you with free consultation and technical support to meet your research needs in the fields of molecular biology, diagnostics and drug discovery. If you have any needs, please feel free to contact us.

Our Services

Services Yield Purification Validation Price
Circular DNA oligonucleotides synthesis 100, 200, 500 pmole HPLC or PAGE MS and PAGE Inquiry
Circular DNA oligonucleotides modified 100, 200, 500 pmole HPLC or PAGE MS and PAGE Inquiry
Circular RNA oligonucleotides synthesis 100, 200, 500 pmole HPLC or PAGE MS and PAGE Inquiry
Circular RNA oligonucleotides modified 100, 200, 500 pmole HPLC or PAGE MS and PAGE Inquiry

Deliverables

Dry powder or solution delivery, according to your needs of the separate packing.
COA files, including original data and the final output excel file etc.

Our Advantages

  • Personalized customization: We can provide a variety of modification types and flexible synthesis specifications.
  • Strict quality control: all circular oligonucleotides products is strictly controlled.
  • Quality analysis: HPLC and MS analysis and QC methods and documents can be provided according to your needs.
  • Professional support: Our team of nucleic acid synthesis experts has many years of experience and provides professional consultation and technical support.
  • Fast delivery: Flexible project arrangement shortens delivery time.
* It should be noted that our service is only used for research, not for clinical use.

Online Inquiry