Chlamydia, a gram-negative pathogen, is a kind of prokaryotic microorganisms. It is a small, non motile group of microorganisms that grow in cells. Chlamydia can be divided into four kinds: Chlamydia pneumoniae, Chlamydia psittaci, Chlamydia trachomatis and Chlamydia bovis. Chlamydia can pass through bacterial filter, parasitize in cells and have a unique development cycle. Chlamydia is a kind of organism smaller than bacteria but larger than virus. It does not have the ability to synthesize high energy compounds ATP and GTP, and must be provided by the host cells. Therefore, it becomes an energy parasite, mostly in the shape of ball and pile, with cell wall and cell membrane.
Fig.1 Life cycle to Chlamydia pneumonia. (Chifiriuc M, et al. 2012)
Chlamydia pneumoniae is considered to be a common cause of pneumonia, bronchitis and other respiratory tract infections. Chlamydia bovis only exists in cattle and sheep. Chlamydia psittaci can cause psittacosis, which is caused by human inhalation of dry dust from the feces of infected birds. Chlamydia trachomatis is not only a cause of trachoma, but also a recognized source of sexually transmitted diseases.
Chlamydia infection requires a certain laboratory test before it can be diagnosed. Polymerase chain reaction (PCR) is a molecular biology inspection method that amplifies the target DNA or RNA sequence with a limited number of samples by a factor of one million, which greatly improves the sensitivity.
The research team of Creative Biogene has rich experience in the field of molecular biology and gene diagnosis. Relying on PCR technology, Creative Biogene can provide you with chlamydia detection from urine or cotton tipped conjunctival swabs.